Weight loss and Weight Chat Blog

December 2, 2008

Understanding biologics: How they differ from drugs and why they cost more

Many of our readers either already have or will in the future encounter the possibility of being treated with a biologic medication. This is because biologics have revolutionized the treatment of such chronic illnesses as rheumatoid arthritis, psoriasis, psoriatic arthritis, Crohn’s disease, and multiple sclerosis, and are widely used in treating a variety of cancers. To name just a few, these products include Enbrel, Humira, Remicade (infliximab), Avonex (inteferon beta-1a), Betaseron (interferon beta-1b), Tysabri, Cimzia (certolizumab pegol), Herceptin (trastuzumab), Rituxan (rituximab), Neupogen (filgrastim), Neulasta (pegfilgrastim) and Leukine (sargramostim). So just what are biologics, how do they differ from more traditional drugs, and why are they so expensive?Although some biologics have been around for a long time, I’m not talking about these first-generation products, which include things like vaccines, blood and blood components. Instead, I’m focusing on the newer, second-generation biologics that have come to market only […]

Original post by natalieb and weightlossopinions.com

February 19, 2008

Rituxan for multiple sclerosis - positive clinical trial results

Rituxan (rituximab) is a biologic medication that is already approved by the FDA for the treatment of both non-Hodgkin’s Lymphoma (NHL) and rheumatoid arthritis (RA). It is now being studied as a potential treatment for multiple sclerosis, and results of an early-stage clinical trial, recently published in the prestigious “New England Journal of Medicine,” show that it may have great potential in treating this chronic illness. This is not the first time that a cancer drug (Rituxan was originally approved for NHL, a type of blood cell cancer) has later been studied in MS. Novantrone (mitoxantrone) is one such cancer drug, originally approved for the treatment of certain leukemias and then later for advanced prostate cancer, which also was eventually approved by the FDA for the treatment of MS.
In the current Phase 2 research, patients, 18-55 years of age with relapsing-remitting MS, were randomized to receive either […]

Original post by admin and weightlossopinions.com

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